Cimetidine inhibits the absorption of protein-bound vitamin B12 but not crystalline vitamin B12

Experiences with dual protein bound aqueous vitamin B12 absorption test in subjects with low serum vitamin B12 concentrations.

A dual isotope vitamin B12 absorption test in which vitamin B12 is given both in aqueous solution and bound to protein (chicken serum), was evaluated in 26 controls and 68 patients with subnormal serum vitamin B12 concentrations (19 with pernicious anaemia, 13 with iron deficiency, seven after partial gastrectomy, seven with malabsorptive states, five with folate deficiency, four with chronic a...

Carbachol and Vitamin B12 Absorption.

Effect of bile on vitamin B12 absorption.

The standard double-isotope Schilling test was used to study vitamin B12 absorption in seven patients with obstructive jaundice and 10 with T-tube bile duct drainage after cholecystectomy and bile duct exploration. In three and five of these patients respectively absorption was impaired. In the second group six patients were restudied after removal of the T tube, and in each case absorption was...

Absorption of vitamin B12 in rheumatoid arthritis.

Since auto-immunity may possibly be a common denominator in pernicious anaemia, thyroid dysfunction, and the rheumatic diseases, the suggested increased incidence ofpernicious anaemia in rheumatoid arthritis (Partridge and Duthie, 1963) is of considerable interest. Their figure of 1 4 per cent., which was five times higher than in their patients with other musculoskeletal disorders, was based o...

Absorption of vitamin B12 in tobacco amblyopia.

In view of the evidence that some abnormality of the metabolism of vitamin B12 is present in tobacco amblyopia (Callender and Denborough, I957; Heaton, McCormick, and Freeman, I958; Chisholm, Bronte-Stewart, and Foulds, I967), it was thought possible that absorption of the vitamin might be reduced in patients with the disease. The patients studied were male pipe smokers with bilateral acquired ...